301120 New understanding of how immune systems differ by sex and change with age

It’s no secret that our immune system function declines as we age, which can make older adults more susceptible to a variety of viral and bacterial pathogens including COVID-19. But the role of sex in immune system aging is not well understood. An NIA-supported study took a closer look at how the timing and degree of aging-related changes in the immune system varies among men and women and identified how particular immunity characteristics diverge as we grow older.